CasNo： 101279-39-4
MF： C10H8BrN
|
General Description |
Quinoline, 6-(bromomethyl)- (6CI,9CI) is a chemical compound categorized under the class of organic compounds known as quinolines and derivatives. Quinolines are compounds containing quinoline, a specific aromatic heterocycle that is structurally characterized by a 2-phenyl-1-benzazepine moiety. Few characteristics of this chemical are its light yellow appearance, low to medium water solubility, and strong acidic nature. Quinoline, 6-(bromomethyl)- (6CI,9CI) is quite reactive and because of this, it is widely used in the synthesis of various chemical products, particularly some pharmaceuticals and dyes. However, due to its potential toxicity, careful handling and adequate protective measures are necessary during its usage. |
InChI:InChI=1/C10H8BrN/c11-7-8-3-4-10-9(6-8)2-1-5-12-10/h1-6H,7H2
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The present invention is directed to cyt...
6-(hydroxymethyl)quinoline
6-bromomethyl quinoline
| Conditions | Yield |
|---|---|
|
With
hydrogen bromide; acetic acid;
at 20 ℃;
for 3h;
|
37.5% |
|
With
hydrogen bromide; acetic acid;
|
|
|
With
water; hydrogen bromide;
at 130 ℃;
|
|
|
6-(hydroxymethyl)quinoline;
With
phosphorus tribromide;
In
benzene;
at 60 ℃;
for 0.75h;
With
water; sodium hydrogencarbonate;
In
benzene;
|
|
|
With
phosphorus tribromide;
In
dichloromethane;
at 20 ℃;
|
6-methylquinoline
6-bromomethyl quinoline
| Conditions | Yield |
|---|---|
|
With
N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile);
In
tetrachloromethane;
for 2h;
Reflux;
|
72.6% |
|
With
N-Bromosuccinimide; dibenzoyl peroxide;
In
tetrachloromethane;
for 2h;
Heating;
|
|
|
With
N-Bromosuccinimide; dibenzoyl peroxide;
In
tetrachloromethane;
for 3h;
Reflux;
|
6-(hydroxymethyl)quinoline
6-methylquinoline
N-Bromosuccinimide
quinoline-6-carbaldehyde
2-(4-methoxy-benzenesulfonyl)-2-methyl-3-quinolin-6-yl-propionic acid ethyl ester
6-phenyl-2-(quinolin-6-ylmethyl)pyridazin-3(2H)-one
