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  • Product Name2-Chloroquinoline
  • CasNo. 612-62-4
  • MFC9H6ClN
  • MW163.606
  • Purity
  • Appearancewhite to yellowish crystals, powder, chunks
  • Packing
  • Contact usInquiry

Product Details

CasNo： 612-62-4

MF： C9H6ClN

Appearance： white to yellowish crystals, powder, chunks

Manufacturer supply good quality 2-Chloroquinoline 612-62-4 with stock

  • Molecular Formula:C9H6ClN
  • Molecular Weight:163.606
  • Appearance/Colour:white to yellowish crystals, powder, chunks 
  • Vapor Pressure:0.0136mmHg at 25°C 
  • Melting Point:34-37 °C(lit.) 
  • Refractive Index:1.652 
  • Boiling Point:267.3 °C at 760 mmHg 
  • PKA:0.41±0.40(Predicted) 
  • Flash Point:141.2 °C 
  • PSA：12.89000 
  • Density:1.27 g/cm3 
  • LogP:2.88820 

2-Chloroquinoline(Cas 612-62-4) Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 67, p. 7884, 2002 DOI: 10.1021/jo016196iSynthesis, p. 1013, 1987 DOI: 10.1055/s-1987-28152

Purification Methods

Purify it by crystallisation of its picrate to constant melting point (123-124o) from *benzene, regenerating the base and distilling it under vacuum [Cumper et al. J Chem Soc 1183 1962]. 2-Chloroquinoline can be crystallised from EtOH. Its picrate has m 123-124o (from EtOH). [Beilstein 20 H 359, 20/7 V 312.]

InChI:InChI=1/C9H6ClN/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H

612-62-4 Relevant articles

Efficient Phosphorus-Free Chlorination of Hydroxy Aza-Arenes and Their Application in One-Pot Pharmaceutical Synthesis

Wang, Jian,Li, Yan-Hui,Pan, Song-Cheng,Li, Ming-Fang,Du, Wenting,Yin, Hong,Li, Jing-Hua

supporting information, p. 146 - 153 (2020/03/10)

The chlorination of hydroxy aza-arenes w...

Environment-friendly preparation method of 2-chloroquinoline

-

Paragraph 0023-0054, (2019/03/08)

The invention discloses an environment-f...

Transition-metal-free decarboxylative halogenation of 2-picolinic acids with dihalomethane under oxygen conditions

Zhang, Xitao,Feng, Xiujuan,Zhang, Haixia,Yamamoto, Yoshinori,Bao, Ming

supporting information, p. 5565 - 5570 (2019/10/22)

A convenient and efficient method for th...

C-Bridged Bispyrrolidines and Bispiperidines as New Ligands

Stumpf, Tim-Daniel J.,Steinbach, Manfred,H?ltke, Magdalene,Heuger, Gerold,Grasemann, Franka,Fr?hlich, Roland,Schindler, Siegfried,G?ttlich, Richard

, p. 5538 - 5547 (2018/10/25)

The preparation of methylene-bridged C2-...

612-62-4 Process route

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Conditions
Conditions Yield
With sulfuryl dichloride;
sulfuryl dichloride
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Conditions
Conditions Yield

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