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  • Product Name8-Hydroxyquinaldine
  • CasNo. 826-81-3
  • MFC10H9NO
  • MW159.188
  • Purity
  • Appearancebeige to brown crystalline powder
  • Packing
  • Contact usInquiry

Product Details

CasNo： 826-81-3

MF： C10H9NO

Appearance： beige to brown crystalline powder

Purity 99% Min 8-Hydroxyquinaldine 826-81-3 Spot Supply with Safe Transportation

  • Molecular Formula:C10H9NO
  • Molecular Weight:159.188
  • Appearance/Colour:beige to brown crystalline powder 
  • Vapor Pressure:0.00508mmHg at 25°C 
  • Melting Point:71-73 °C(lit.) 
  • Refractive Index:1.666 
  • Boiling Point:267 °C at 760 mmHg 
  • PKA:pK1:5.55(＋1);pK2:10.31(0) (25°C) 
  • Flash Point:139.4 °C 
  • PSA：33.12000 
  • Density:1.21 g/cm3 
  • LogP:2.24880 

8-Hydroxyquinaldine(Cas 826-81-3) Usage

Preparation

8-hydroxyquinaldine is obtained from the reaction of 2-aminophenol with crotonaldehyde. Mix 2-aminophenol and 2-Nitrophenol homogeneously and add hydrochloric acid. Add crotonaldehyde under stirring. Heat for 6h and leave overnight. Distill the reacted o-nitrophenol by water distillation, and add sodium hydroxide solution to the residual solution to make it weakly basic. Then add powdered carbonyls for saturation, and distill 8-Hydroxyquinaldine by water distillation, and then distill the crude product under reduced pressure and recrystallize it with ethanol to obtain 8-hydroxyquinaldine.

General Description

2-Methyl-8-quinolinol is a methyl substituted quinolinol derivative that shows fungicidal property. It can also undergo complexation with transition metal complexes.

Purification Methods

Crystallise the quinoline from EtOH or aqueous EtOH. Its solubility at 20o in H2O is 0.366g/L, and in CHCl3 it is 466g/L. It complexes with many metals. [Beilstein 21 H 106, 21 III/IV 2132.]

InChI:InChI=1/C10H9NO/c1-7-5-6-8-3-2-4-9(12)10(8)11-7/h2-6,12H,1H3

826-81-3 Relevant articles

-

Phillips et al.

, p. 1033 (1952)

-

Nickel-Catalyzed Dehydrogenation of N-Heterocycles Using Molecular Oxygen

Banerjee, Debasis,Bera, Atanu,Bera, Sourajit

supporting information, (2020/09/02)

Herein, an efficient and selective nicke...

Method of preparing 8-hydroxy-2-methylquinoline by utilizing chlorquinaldol waste residues

-

Paragraph 0026-0027; 0029-0030; 0032-0033; 0034-0036; 0038-0, (2018/09/11)

The invention belongs to the technical f...

Study on Relationship Between Fluorescence Properties and Structure of Substituted 8-Hydroxyquinoline Zinc Complexes

Jianbo, He,Tingting, Zhou,Yongjing, Cao,Yuanyuan, Zhang,Weiqing, Yang,Menglin, Ma

, p. 1121 - 1126 (2018/08/17)

Organic light-emitting diodes (OLEDs) pr...

Microwave-enhanced Friedl?nder synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and tolerant bacteria

Garrison, Aaron T.,Abouelhassan, Yasmeen,Yang, Hongfen,Yousaf, Hussain H.,Nguyen, Tho J.,Huigens, Robert W.III.

, p. 720 - 724 (2017/04/27)

Herein, we disclose the development of a...

826-81-3 Process route

2-methyl-8-quinolinyl-β-D-glucopyranoside
1419402-08-6

2-methyl-8-quinolinyl-β-D-glucopyranoside

2-methyl-8-quinolinol
826-81-3

2-methyl-8-quinolinol

β-D-glucose
492-61-5

β-D-glucose

Conditions
Conditions Yield
With β-glucosidase from almonds; water; In aq. phosphate buffer; at 37 ℃; for 4h; pH=7.4; Reagent/catalyst; Enzymatic reaction;
chloroquinaldol
72-80-0

chloroquinaldol

2-methyl-8-quinolinol
826-81-3

2-methyl-8-quinolinol

Conditions
Conditions Yield
With palladium hydroxide 10 wt. % on activated carbon; hydrogen; triethylamine; In ethanol; at 43 ℃; for 6h; under 9750.98 - 11251.1 Torr; Solvent; Reagent/catalyst; Pressure;
62.67%

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