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  • Product Name2-Quinolinol
  • CasNo. 59-31-4
  • MFC9H7NO
  • MW145.161
  • Purity
  • Appearancewhite to light purple or purple-brownish powder
  • Packing
  • Contact usInquiry

Product Details

CasNo： 59-31-4

MF： C9H7NO

Appearance： white to light purple or purple-brownish powder

Manufacturer supply top purity 2-Quinolinol 59-31-4 with ISO standards

  • Molecular Formula:C9H7NO
  • Molecular Weight:145.161
  • Appearance/Colour:white to light purple or purple-brownish powder 
  • Vapor Pressure:5.67E-05mmHg at 25°C 
  • Melting Point:198-199 °C(lit.) 
  • Refractive Index:1.595 
  • Boiling Point:346.7 °C at 760 mmHg 
  • PKA:-0.31, 11.76(at 20℃) 
  • Flash Point:200.6 °C 
  • PSA：32.86000 
  • Density:1.188 g/cm3 
  • LogP:1.52810 

2-Quinolinol(Cas 59-31-4) Usage

Synthesis Reference(s)

Synthesis, p. 739, 1975 DOI: 10.1055/s-1975-23918

Purification Methods

Crystallise it from MeOH. It has m 200-201o after sublimation in a vacuum. The picrate has m 132o after crystallisation from Et2O. [Gibson et al. J Chem Soc 4340 1955, Beilstein 21 III/IV 1057, 21/8 V 217.]

Definition

ChEBI: A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.

General Description

2-Hydroxyquinoline is a specific inhibitor of plaque paraoxonase1 (PON1).

InChI:InChI=1/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

59-31-4 Relevant articles

-

Miller et al.

, p. 4763 (1950)

-

A photochemical C=C cleavage process: Toward access to backbone N-formyl peptides

Ball, Zachary T.,Wang, Haopei

supporting information, p. 2932 - 2938 (2022/01/12)

Photo-responsive modifications and photo...

Site-Selective Acceptorless Dehydrogenation of Aliphatics Enabled by Organophotoredox/Cobalt Dual Catalysis

Zhou, Min-Jie,Zhang, Lei,Liu, Guixia,Xu, Chen,Huang, Zheng

supporting information, p. 16470 - 16485 (2021/10/20)

The value of catalytic dehydrogenation o...

Iron-Catalyzed ?±,?-Dehydrogenation of Carbonyl Compounds

Zhang, Xiao-Wei,Jiang, Guo-Qing,Lei, Shu-Hui,Shan, Xiang-Huan,Qu, Jian-Ping,Kang, Yan-Biao

supporting information, p. 1611 - 1615 (2021/03/03)

An iron-catalyzed α,β-dehydrogenation of...

Efficient visible light mediated synthesis of quinolin-2(1H)-ones from quinolineN-oxides

Bhuyan, Samuzal,Chhetri, Karan,Hossain, Jagir,Jana, Saibal,Mandal, Susanta,Roy, Biswajit Gopal

supporting information, p. 5049 - 5055 (2021/07/29)

Quinolin-2(1H)-ones are one of the impor...

59-31-4 Process route

4-methoxy-benzoyl chloride
100-07-2

4-methoxy-benzoyl chloride

1-hydroxycarbostyril
58-57-1

1-hydroxycarbostyril

2-quinolone
59-31-4,70254-42-1,493-62-9

2-quinolone

4-methoxybenzoic acid
100-09-4

4-methoxybenzoic acid

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 12 h / 20 °C
2: water; methanol / UV-irradiation; Photolysis
With triethylamine; In methanol; dichloromethane; water;
1-(p-methoxybenzoyloxy)-2(1H)-quinolone
1404369-03-4

1-(p-methoxybenzoyloxy)-2(1H)-quinolone

2-quinolone
59-31-4,70254-42-1,493-62-9

2-quinolone

4-methoxybenzoic acid
100-09-4

4-methoxybenzoic acid

Conditions
Conditions Yield
In methanol; water; Quantum yield; UV-irradiation; Photolysis;
85%

59-31-4 Upstream products

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59-31-4 Downstream products

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    2-ethoxyquinoline

  • 53761-50-5
    53761-50-5

    1-Ethyl-1,2-dihydrochinolin-2-on

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    612-62-4

    2-Chloroquinoline

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    635-46-1

    1,2,3,4-tetrahydroisoquinoline

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