CasNo： 21302-43-2
MF： C9H10Cl2N2O
Appearance： yellow to brown crystalline powder
InChI:InChI=1/C9H8N2O.2ClH/c10-7-3-4-8(12)9-6(7)2-1-5-11-9;;/h1-5,12H,10H2;2*1H
5-(p-Tolylsulfonylimino)quinolin-8-one w...
Base mediated condensation reaction betw...
Two substituted oxines, nitroxoline (5) ...
Novel 6,7-disubstituted-5,8-quinolinedio...
nitroxoline
5-amino-8-hydroxyquinoline dihydrochloride
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride; hydrogen;
palladium on activated charcoal;
In
water;
for 1.5h;
under 2280 Torr;
|
97% |
|
With
hydrogenchloride; palladium 10% on activated carbon; hydrogen;
In
water;
at 70 ℃;
for 18h;
under 4395.87 Torr;
|
95% |
5-Nitroso-8-hydroxyquinoline hydrochloride
5-amino-8-hydroxyquinoline dihydrochloride
| Conditions | Yield |
|---|---|
|
5-Nitroso-8-hydroxyquinoline hydrochloride;
With
sodium hydroxide; sodium dithionite;
In
water;
at 75 - 80 ℃;
With
hydrogenchloride; water;
at 50 ℃;
|
69% |
|
With
hydrogenchloride; tin(ll) chloride;
for 1h;
|
13.7 g |
|
5-Nitroso-8-hydroxyquinoline hydrochloride;
With
sodium dithionite; sodium hydroxide;
In
water;
at 40 - 80 ℃;
Inert atmosphere;
With
hydrogenchloride;
In
water;
at 50 ℃;
Inert atmosphere;
|
nitroxoline
5-Nitroso-8-hydroxyquinoline hydrochloride
8-quinolinol
4,5-dihydro-4,5-dioxo-1H-pyrrolo<2,3-f>quinoline-2-carboxylic acid
C19H11N3O3
6,7-dichloroquinoline-5,8-dione
6,7-Dibrom-5,8-dihydrochinolin-5,8-dion
